Flávio A Amaral Selected Research

N(4)- (2,2- dimethyl- 1- methylcarbamoylpropyl)- N(1)- hydroxy- 2- hydroxymethyl- 3- phenylsuccinamide

9/2007

Effects of PKF242-484 and PKF241-466, novel dual inhibitors of TNF-alpha converting enzyme and matrix metalloproteinases, in a model of intestinal reperfusion injury in mice.

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Flávio A Amaral Research Topics

Disease

19	Inflammation (Inflammations) 11/2021 - 12/2007
9	Gout 01/2022 - 02/2012
6	Arthritis (Polyarthritis) 01/2021 - 08/2008
5	Pain (Aches) 01/2022 - 06/2014
5	Hyperalgesia 08/2019 - 07/2014
4	Infections 01/2018 - 12/2011
4	Ischemia 12/2007 - 02/2007
3	Edema (Dropsy) 08/2019 - 06/2014
3	Hemorrhage 12/2007 - 02/2007
3	Reperfusion Injury 09/2007 - 02/2007
2	Bone Resorption 01/2021 - 12/2016
2	Osteoarthritis 01/2021 - 12/2016
2	Neoplasms (Cancer) 01/2016 - 02/2007
1	Gouty Arthritis 01/2022
1	Multiple Organ Failure (MODS) 01/2018
1	Infectious Arthritis (Septic Arthritis) 01/2018
1	Sepsis (Septicemia) 01/2018
1	Experimental Arthritis 01/2016
1	Nociceptive Pain 06/2014
1	Necrosis 01/2011
1	Fibrosis (Cirrhosis) 04/2009
1	Pulmonary Fibrosis (Fibrosing Alveolitis) 04/2009
1	Pneumonia (Pneumonitis) 04/2009
1	Wounds and Injuries (Trauma) 09/2007

Drug/Important Bio-Agent (IBA)

9	Uric Acid (Urate)IBA 01/2022 - 06/2015
6	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 08/2019 - 02/2007
6	CytokinesIBA 01/2019 - 02/2007
4	AntigensIBA 08/2017 - 08/2008
4	InflammasomesIBA 05/2017 - 02/2012
3	Interleukin-10 (Interleukin 10)IBA 01/2021 - 02/2012
3	CarrageenanIBA 08/2019 - 06/2014
3	ChemokinesIBA 01/2018 - 08/2017
3	Chemokine ReceptorsIBA 01/2018 - 08/2008
2	2-phthalimidethanolIBA 08/2017 - 07/2014
2	hydroxide ionIBA 08/2017 - 07/2014
2	2-phthalimidethyl nitrateIBA 08/2017 - 07/2014
2	Opioid Analgesics (Opioids)IBA 05/2017 - 06/2014
2	Messenger RNA (mRNA)IBA 05/2017 - 01/2016
2	Narcotic Antagonists (Opioid Antagonists)IBA 05/2017 - 06/2014
2	Acetates (Acetic Acid Esters)FDA Link 01/2017 - 06/2015
2	Annexin A1IBA 01/2017 - 01/2017
2	Proteins (Proteins, Gene)FDA Link 01/2017 - 01/2016
1	tyrosine receptor (receptor, tyrosine)IBA 11/2021
1	c-Mer Tyrosine KinaseIBA 11/2021
1	Captopril (Capoten)FDA LinkGeneric 01/2021
1	Angiotensin IIIBA 01/2021
1	Hydrogen Sulfide (Sulfide, Hydrogen)IBA 08/2019
1	4-methylbenzenecarbothioamideIBA 08/2019
1	Formaldehyde (Formol)FDA Link 08/2019
1	Phosphotransferases (Kinase)IBA 01/2019
1	PTX3 proteinIBA 01/2019
1	Chemokine CXCL1IBA 01/2018
1	methylated bovine serum albumin (MBSA)IBA 08/2017
1	AntioxidantsIBA 05/2017
1	Analgesics (Analgesic Drugs)IBA 05/2017
1	Superoxides (Superoxide)IBA 05/2017
1	QuercetinIBA 05/2017
1	Naloxone (Narcan)FDA LinkGeneric 05/2017
1	Dietary Fiber FDA Link 01/2017
1	Volatile Fatty AcidsIBA 01/2017
1	Antigen-Antibody Complex (Immune Complex)IBA 01/2017
1	GlucocorticoidsIBA 01/2017
1	Pharmaceutical PreparationsIBA 12/2016
1	Mefenamic Acid (Pontal)FDA Link 12/2016
1	Proteoglycans (Proteoglycan)IBA 12/2016
1	Etanercept (Enbrel)FDA Link 01/2016
1	Biological ProductsIBA 01/2016
1	Glucose (Dextrose)FDA LinkGeneric 01/2016
1	LipidsIBA 01/2016
1	LipopolysaccharidesIBA 01/2016
1	Chemokine CXCL12IBA 01/2016
1	AdipokinesIBA 01/2016
1	glutarimideIBA 07/2014
1	phthalimideIBA 07/2014
1	Thalidomide (Thalomid)FDA Link 07/2014
1	Cyproheptadine (Periactin)FDA Link 06/2014
1	azadirachtin (azadirachtin A)IBA 06/2014
1	Naltrexone (ReVia)FDA LinkGeneric 06/2014
1	ZymosanIBA 06/2014
1	Arachidonate 5-Lipoxygenase (5 Lipoxygenase)IBA 02/2012
1	Leukotriene B4IBA 02/2012
1	Interleukin-18 (Interleukin 18)IBA 12/2011
1	Nitric Oxide Synthase (NO Synthase)IBA 12/2011
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/2011
1	Interleukin-12 (IL 12)IBA 12/2011
1	InterleukinsIBA 01/2011
1	Bleomycin (Blenoxane)FDA LinkGeneric 04/2009
1	4-(2-amino-1-methyl-2-oxoethyl)phenyl trifluoromethanesulfonateIBA 04/2009
1	CollagenIBA 04/2009
1	Interleukin-13IBA 04/2009
1	indium-bleomycinIBA 04/2009
1	Interleukin-8B ReceptorsIBA 08/2008
1	Protein Isoforms (Isoforms)IBA 12/2007
1	Matrix Metalloproteinase InhibitorsIBA 09/2007
1	Dihydrotachysterol (AT 10)IBA 09/2007
1	Matrix Metalloproteinases (MMPs)IBA 09/2007
1	ADAM17 ProteinIBA 09/2007
1	N(4)- (2,2- dimethyl- 1- methylcarbamoylpropyl)- N(1)- hydroxy- 2- hydroxymethyl- 3- phenylsuccinamideIBA 09/2007

Therapy/Procedure

1	Therapeutics 01/2022
1	Intra-Articular Injections 08/2017